Conference - "Cell-Free Protein Expression Systems for Decentralized Biomanufacturing", by Katherine Warfel (Northwestern University, Evanston, IL, Etats-Unis)

on the May 13, 2022

11.00 am
Salle des séminaires IBS


Free participation
Access to the EPN campus requires an appointment notice, please ask for it, at least 48 hours in advance at ibs.seminaires@ibs.fr




 
Katherine Warfel from the Northwestern University, Evanston, IL, USA, in Chemical and Biological Engineering (Jewett Lab), will give a conference "Cell-Free Protein Expression Systems for Decentralized Biomanufacturing " on Friday, May 13th, 2022 at 11.00 am in Institut de Biologie Structurale (IBS), Grenoble Presqu'Île.

E. coli cell-free expression (CFE) systems have been widely adopted in recent years for prototyping and biomanufacturing due to their ease-of-use and control over reaction conditions. By supplementing resources for transcription and translation to a soluble cell extract, cell-free systems can be used to produce proteins directly in vitro from DNA templates.
Cell-free expression systems provide a modular, flexible, and scalable biomanufacturing platform without the viability constraints imposed by living cells. Additionally, CFE reactions can be easily lyophilized and reconstituted, making them a versatile platform for production of diagnostics and therapeutics at the point of care.
However, increased robustness such as low reaction cost and high thermostability are necessary for further technology adoption and implementation as a decentralized biomanufacturing strategy.


Hôte : R. Vivès (IBS/Groupe Structure et Activité des Glycosaminoglycanes)


 

Published on May 3, 2022

Practical informations

Location


Seminar Room IBS
Institut de biologie structurale
71 avenue des Martyrs
38000 Grenoble
T.+33 (0)4 57 42 85 00
www.ibs.fr
Access to the EPN campus requires an appointment notice, please ask for it, at least 48 hours in advance at ibs.seminaires@ibs.fr