Glyco@Seminar: Sebastian Cerminati

on the June 21, 2019

June 21th, 11:00 am
Sebastian Cerminati from CONICET Argentina Science and Technology Council (Argentina) will give a talk about “High level expression of industrially relevant proteins and products”.
Abstract

In the last decades, the development of genetic engineering tools and fermentation technologies facilitated the cost-efficient manufacturing of recombinant proteins and relevant industrial products. Today, there are over 500 enzymes used in the food, cleaning, chemical and pharmaceutical industries. The use of enzymes in the industry offers an environmental friendly solution over traditional chemical processes.
In the last few years, there has been a constant increase in the demand for oils to be used as a food and production of fuels. This demand has generated a need for cost-effective methods for removing contaminating phospholipids from crude oils, known as gums, during the refining process. Here, it is describe the recombinant production, the expression optimization, and the development of high cell density cultures for producing  two different phospholipases designed to be used combined for hydrolyzing 90% of the phospholipids present in soy-bean oil.
Furthermore, as part of the development of a Bacillus platform for industrial relevant compounds production, we have engineered an auxotrophic Bacillus hyaluronic acid (HA) producing strain which may be employed to produce high-quality safe HA at industrial scale.




 

Published on May 28, 2019

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Cermav, Chartreuse room
601 rue de la Chimie
Campus universitaire