Thesis defense: Erwan Gicquel

on the December 1, 2017

At 9:30 a.m.
Erwan Gicquel from LGP2 will defend his thesis : "Development of stimuli-responsive cellulose nanocrystals hydrogels for smart applications". His thesis director is Julien Bras.
This project consists to develop and study new hybrid structures based on nanocelluloses and stimuli-responsive polymers, in particular, thermo-responsive polymers. Nanocelluloses - nanoparticles extracted from cellulose - exist in two forms: cellulose nanocrystals (CNCs) and cellulose nanofibrils (CNFs). This study focused on the design of CNCs hydrogels with stimuli-responsive polymers. Several thermo-responsive polymers have been used for their biocompatibility and lower critical solution temperature (LCST) close to body temperature. This work consisted of (i) preparation of systems using the principles of green chemistry, (ii) the rheological study of these thermo-sensitive hydrogels, and (iii) the development of smart applications for these unique biomaterials. Through the use of state of the art technologies (SANS, SAXS), physicochemical interactions between the polymers and CNCs have been studied. The use of block copolymers made it possible to create CNCs-based hydrogels with specific rheological properties: liquid at ambient temperature to gel at body temperature. These hydrogels can be used in the creation of injectable systems for biomedical applications, as well as thermosensitive surfaces.

Key-words: Cellulose nanocrystals, hydrogel, thermo-responsive, stimuli-responsive

Published on August 23, 2018

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LGP2 - Grenoble - salle D2