Thesis defense: Maxime LEPRINCE

on the September 24, 2021

September 24
Maxime Leprince is defending his thesis "Design of conductive inks and polysaccharide-based hydrogels for the development of biodegradable devices in a controlled manner" on 24 September. He carried out this work in co-supervision with the CERMAV (under the co-direction of Pr Rachel Auzély) and the CEA - Département Technologies Biologie et Santé "DTBS", Laboratoire Chimie Capteurs et Biomatériaux "L2CB" (under the co-direction of Dr Isabelle Texier-Nogue).
Research on flexible biocompatible conductive materials has been burgeoning over the last decades due to the huge number of applications in bioelectronics. Recently, conductive bioelectronic devices based on commercial PEDOT:PSS (3,4-poly(ethylenedioxythiophene) : poly(styrene sulfonate) have been developed, using conductive hydrogels as contact electrodes. The soft and flexible nature of these polymer networks make them suitable candidates for electronics/soft tissue interface. However, those conductive materials display some limitations for in vivo implantation due to problems of biocompatibility and biodegradability of PSS.
In this work, we aimed to replace PSS by a modified hyaluronic acid (HA) derivative to develop a new biocompatible and degradable PEDOT dopant. This HA derivative enabled to design a new biocompatible, degradable, printable and cross-linkable PEDOT-based ink, and as well, served as an extracellular-matrix-mimicking building block for the construction of pure conductive hydrogels. These properties could enable the design of soft transient electronic devices, which could avoid implant removal surgery.

It will happen on Zoom. Link to be asked from: anne.imberty(at)
Published on September 17, 2021