Work-package 4 will develop new technologies for the detection and characterization of glyco-compounds and libraries of compounds for long term use. The developments in synthetic and analytical methods, and the set-up of glycoscience databases will provide a tool-kit for the community
Objectives
to provide the community with panels of biomolecules for research in glycosciences;
to develop tools for characterizing single objects such as glycomolecules, glycoconjugates, lectins, glyco-enzymes;
to improve structural approaches for solving the structure of complex glycans and their interactions with receptors.
Description of the work
Task 1: Production and engineering of glycans and glycan-acting proteins.
Task 2: Novel analytical methods for characterizing glycomolecules.
Task 3: Improving methods for solving the structure of glycans and complexes with receptors.