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Thesis defense: Ons Dakhlaoui


On September 7, 2023

Grenoble - Presqu'île


Ons Dakhlaoui will defend her thesis "Improving selective DNP (SelDNP) for biomolecular applications" on Thursday 07 septembre 2023 - 14:30, Salle Chrome 1 Minatec

Dynamic nuclear polarization (DNP) is a hyperpolarization technique that improves the sensitivity of solid-state nuclear magnetic resonance (NMR) experiments. However, its use for biomolecules is limited by line broadening and loss of resolution induced by the freezing of local dynamics at the cryogenic temperature required for DNP, resulting in conformational heterogeneity. To overcome this problem, the thesis presents solution through introduction of  a selective DNP methodology (SelDNP), which recovers highly resolved spectra specific to protein binding sites.

The research was performed at MEM-CEA and CERMAV-CNRS under the supervisio of Dr Sabine Hediger and Dr. Anne Imberty, and was funded by Labex ARCANE


On September 7, 2023
Complément date

2:30 pm


Grenoble - Presqu'île

Complément lieu

Salle Chrome 1 Minatec
3 Parvis Louis Néel

Submitted on September 26, 2023

Updated on September 26, 2023